• Localized Therapy of Vaginal Infections and Inflammation: Liposomes-In-Hydrogel Delivery System for Polyphenols 

      Jøraholmen, May Wenche; Basnet, Purusotam; Tostrup, Mia; Moueffaq, Sabrin; Skalko-Basnet, Natasa (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-27)
      Natural polyphenols, such as resveratrol (RES) or epicatechin (EPI), are attractive for treatments of various diseases, including vaginal infections and inflammation, because of their strong anti-oxidative and anti-inflammatory properties. However, their low solubility and consequent poor bioavailability limit their therapeutic uses. To overcome these limitations, a vaginal delivery system comprising ...
    • Topical vaginal therapy: Development of a liposomal hydrogel delivery system for epicatechin 

      Moueffaq, Sabrin (Mastergradsoppgave; Master thesis, 2018-05-15)
      Vaginal infections are common in women of all ages and proper treatment is essential. The vaginal route of administration can be considered as favourable for the local therapy of vaginal infections. There are several vaginal dosage forms currently available; however, all suffer from limitations such as leakage and limited residence time at the site of action resulting in reduced therapeutic effect. ...